TRANZFORMER Platform
Designed with developability in mind
AN ANTIBODY PLATFORM FEATURING INTERCHANGEABLE BINDERS ADAPTABLE TO MULTIPLE DISEASES
Quieting the body’s alarms
Targeting multiple pathways activated in inflammatory diseases
Activating immune checkpoints and blocking activating receptors
Turning cold tumors hot
Targeting multiple pathways in the TME, retained at the site of the tumor mass
Activating immune cells while simultaneously inhibiting immune checkpoints
LOCALLY RE-EDUCATING IMMUNE CELLS TO DRIVE SYSTEMIC TUMOR DESTRUCTION
Designed for locoregional delivery in lung tumors
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Activation of T cells, NK cells, and APCs within the TME
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Converts immune-cold tumors into immune-active tissue